Do you hear that alot? I do.. I have a great big family! My kids, plus 18 nieces and nephews, and 5 brothers and sisters and their spouses! Plus mom and dad, gramma, aunts, uncles etc.. I wish I could give a gift to everyone but I simply can't afford it.
At the first of each month, I look up and see who has birthdays. I then go to my trusty "card box" and pull out appropriate card for each person. (If there are anniversaries I grab cards for those too.)
I fill out the cards, address them and stamp them. BUT I DON"T mail them. I slip them into my daily planner about a week before the event and send them then. Super easy!
Also- Inside of my "card box" I have lots of files listing blank cards, birthday cards, anniversary cards, thank you cards and sympathy cards.